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M35.81

Billable

Multisystem inflammatory syndrome

M35.81 is the ICD-10-CM code for Multisystem inflammatory syndrome. It is a billable, specific code valid for reimbursement.

Status
Billable
Chapter
M00-M99
Parent
M35.8
Edition
FY2026

M00-M99 Diseases of the musculoskeletal system and connective tissue

Includes

  • •MIS-A
  • •MIS-C
  • •Multisystem inflammatory syndrome in adults
  • •Multisystem inflammatory syndrome in children
  • •Pediatric inflammatory multisystem syndrome
  • •PIMS

Code first

  • •, if applicable, COVID-19 (U07.1)

Use additional code

  • •code, if applicable, for:
  • •exposure to COVID-19 or SARS-CoV-2 infection (Z20.822)
  • •personal history of COVID-19 (Z86.16)
  • •post COVID-19 condition (U09.9)

Notes

  • •any associated complications such as:
  • •acute hepatic failure (K72.0-)
  • •acute kidney failure (N17.-)
  • •acute myocarditis (I40.-)
  • •acute respiratory distress syndrome (J80)
  • •cardiac arrhythmia (I47-I49.-)
  • •pneumonia due to COVID-19 (J12.82)
  • •severe sepsis (R65.2-)
  • •viral cardiomyopathy (B33.24)
  • •viral pericarditis (B33.23)

Frequently asked questions

What is ICD-10 code M35.81?
M35.81 is the ICD-10-CM code for "Multisystem inflammatory syndrome". It falls under M00-M99 Diseases of the musculoskeletal system and connective tissue.
Is M35.81 a billable code?
Yes — M35.81 is a billable, specific ICD-10-CM code valid for reimbursement.

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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