D81.81

Non-billable

Biotin-dependent carboxylase deficiency

D81.81 is the ICD-10-CM code for Biotin-dependent carboxylase deficiency. It is a non-billable category code — use a more specific child code such as D81.810 for billing.

Status
Header (non-billable)
Chapter
D50-D89
Parent
D81.8
Subcodes
3
Edition
FY2026

D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Includes

  • Multiple carboxylase deficiency

Excludes1 — not coded here

  • biotin-dependent carboxylase deficiency due to dietary deficiency of biotin (E53.8)

Frequently asked questions

What is ICD-10 code D81.81?
D81.81 is the ICD-10-CM code for "Biotin-dependent carboxylase deficiency". It falls under D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.
Is D81.81 a billable code?
No — D81.81 is a non-billable header code. Use a more specific child code (such as D81.810) for billing.
What are the subcodes of D81.81?
D81.81 has 3 more specific child codes, including D81.810, D81.818, D81.819.
What is excluded from D81.81?
Excludes1 (not coded here): biotin-dependent carboxylase deficiency due to dietary deficiency of biotin (E53.8).

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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