D75.81

Billable

Myelofibrosis

D75.81 is the ICD-10-CM code for Myelofibrosis. It is a billable, specific code valid for reimbursement.

Status
Billable
Chapter
D50-D89
Parent
D75.8
Edition
FY2026

D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Includes

  • Myelofibrosis NOS
  • Secondary myelofibrosis NOS

Excludes1 — not coded here

  • acute myelofibrosis (C94.4-)
  • idiopathic myelofibrosis (D47.1)
  • leukoerythroblastic anemia (D61.82)
  • myelofibrosis with myeloid metaplasia (D47.4)
  • myelophthisic anemia (D61.82)
  • myelophthisis (D61.82)
  • primary myelofibrosis (D47.1)

Code first

  • the underlying disorder, such as:
  • malignant neoplasm of breast (C50.-)

Use additional code

  • code, if applicable, for associated therapy-related myelodysplastic syndrome (D46.-)
  • code for adverse effect, if applicable, to identify drug (T45.1X5)

Frequently asked questions

What is ICD-10 code D75.81?
D75.81 is the ICD-10-CM code for "Myelofibrosis". It falls under D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.
Is D75.81 a billable code?
Yes — D75.81 is a billable, specific ICD-10-CM code valid for reimbursement.
What is excluded from D75.81?
Excludes1 (not coded here): acute myelofibrosis (C94.4-); idiopathic myelofibrosis (D47.1); leukoerythroblastic anemia (D61.82); myelofibrosis with myeloid metaplasia (D47.4).

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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