D57.45

Non-billable

Sickle-cell thalassemia beta plus with crisis

D57.45 is the ICD-10-CM code for Sickle-cell thalassemia beta plus with crisis. It is a non-billable category code — use a more specific child code such as D57.451 for billing.

Status
Header (non-billable)
Chapter
D50-D89
Parent
D57.4
Subcodes
6
Edition
FY2026

D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Includes

  • HbS-beta plus with crisis
  • Sickle-cell beta plus with crisis

Frequently asked questions

What is ICD-10 code D57.45?
D57.45 is the ICD-10-CM code for "Sickle-cell thalassemia beta plus with crisis". It falls under D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.
Is D57.45 a billable code?
No — D57.45 is a non-billable header code. Use a more specific child code (such as D57.451) for billing.
What are the subcodes of D57.45?
D57.45 has 6 more specific child codes, including D57.451, D57.452, D57.453.

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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